Seattle-Denver Center of Innovation (COIN)

COIN Investigators & Staff

COIN Investigators

David Au, MD, MS

Title: Core Investigator
Professor, University of Washington School of Medicine, Co-Director, Clinical Research Training Program, Division of Pulmonary and Critical Care Medicine

Contact: David.Au@va.gov

Location: Seattle

University of Washington webpage

See Dr. Au's Dimensions profile that includes: publications, grants, datasets, patents and clinical trials

I am a pulmonary and critical care physician and have had a long interest in improving delivery of care to patients with COPD and lung cancer. I have particular interest in improving the reach of specialty care medicine, especially at the population level. My program has a strong emphasis in facilitating delivery and quality of care in the outpatient setting and in the primary care environment where quality of lung disease care is consistently poor. I have led a number of initiative to improve access and quality of healthcare delivery in both research and operational projects.

My search program has included diverse areas including focusing on comparative effectiveness, being a founding member of the CONCERT-CER network that led efforts at developing national CER priorities for COPD. More recently, we have focused on operationally relevant and pragmatic clinical trials targeting high impact conditions including overuse of medical services, COPD and obesity. Having roots as part of the Office of Specialty Care Evaluation Center and with a number of colleagues from Seattle, Denver and Cleveland, we have established the VA collaborative evaluation (VACE) center that seeks to provide our organizational partner with strategic information about VA healthcare delivery.

Operationally, I established the Pulmonary/Sleep specialty Care Access Network, Extension of Community Healthcare Outcomes for VISN20 (now VA ECHO) and worked within VA Office of Veteran Access to Care (OVAC) to help conceptualize access and implement a new referral management process. I have been fortunate to be engaged with numerous organizations including Chairing the FDA Pulmonary, Allergy Drugs Advisory Committee, NCQA respiratory measurement assessment panel and VA's Pulmonary Field Advisory Committee. I have been engaged with the American Thoracic Society including chairing the ATS international meeting, behavioral sciences and health services assembly, among others. I recently rotated off the ABIM pulmonary board exam writing committee. I am an active member of the UW Pulmonary, Critical Care and Sleep Medicine Faculty where I serve on the Steering Committee of our T32 program and am the MPI of an NHLBI K12 in implementation.

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Grants & Funding

Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD -- EQuiP COPD

Role: Co-PI with Lucas Donovan
The study team will conduct this clinical trial at five medical centers and 38 associated clinics within the Department of Veterans Affairs (VA) in Washington, Oregon, Minnesota, and Massachusetts.
The study will recruit at least 200 PCPs. It will randomly assign them to population management by either pulmonary specialists or pharmacists.
The team will then look at the participating PCP’s patient panels to identify patients with COPD who might benefit from better care quality.
Pulmonary specialists and pharmacists will review patients based on the group to which their PCP is assigned.
After review, pulmonary specialists and pharmacists will then deliver evidence-based recommendations to PCPs along with unsigned orders to streamline care. The study team expects to provide guidance to at least 4,000 patients.
Primary outcomes will be:
(1) the percentage of guideline-recommended therapies that patients receive as measured from the medical record,
(2) quality of life as measured by the Clinical COPD Questionnaire, and
(3) whether patients experience a COPD exacerbation, lung infections, hospitalization, or death as measured from medical records.
Secondary outcomes will include how often PCPs accept recommendations and how often patients experience each outcome noted above.
PCORI Website

University of Washington Implementation Science Training Program (UW-ISTP)K12

Advances in modern medicine often need to be translated into clinical practice. The University of Washington Implementation Science Program aims to train future implementation scientists focused on pulmonary, critical care, and palliative care medicine.
Ultimately, the program will improve population health by using implementation science to expedite the adoption of evidence-based care.
Funder: National Heart, Lung, and Blood Institute
NIH website
Publications of note:
Assessment of Natural Language Processing of Electronic Health Records to Measure Goals-of-Care Discussions as a Clinical Trial Outcome
Efficacy and Conflicts of Interest in Randomized Controlled Trials Evaluating Headspace and Calm Apps: Systematic Review
Advance Care Planning Documentation and Intensity of Care at the End of Life for Adults with Congestive Heart Failure, Chronic Kidney Disease, and Both Illnesses

AdvanCing High quality COPD care for people with immune dysfunction by implementing Evidence-based management through proactive E-consults (ACHIEVE)

Role: Co-PI with Christian Helfrich; David Au is PI
Chronic obstructive pulmonary disease (COPD) is common and associated with morbidity and mortality in HIV-infected patients. However, COPD is often underdiagnosed, and care is suboptimal.
We propose to test an intervention to proactively support primary care providers of HIV-infected patients and make evidence-based recommendations to improve the care and health of their patients with COPD.
Funder: National Heart, Lung, and Blood Institute
NIH website
Publications of note:
A cross-sectional analysis of diagnosis and management of chronic obstructive pulmonary disease in people living with HIV
Receipt and Predictors of Smoking Cessation Pharmacotherapy among Veterans With and Without HIV
ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (The PRECluDE Consortium): Combatting Chronic Disease Comorbidities in HIV Populations through Implementation Research
Community‐Acquired Pneumonia and Risk of Cardiovascular Events in People Living With HIV

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Recent Publications

2024

Spece LJ, Hee Wai T, Donovan LM, Duan KI, Plumley R, Crothers KA, Thakur N, Baugh A, Hayes S, Picazo F, Feemster LC, Au DH. The Impact of Changing Race-Specific Equations for Lung Function Tests among Veterans with COPD. Ann Am Thorac Soc. 2024 May 31. doi: 10.1513/AnnalsATS.202312-1020OC. Epub ahead of print.
PMID: 38820262.

Morenz AM, Liao JM, Au DH, Hayes SA. Area-Level Socioeconomic Disadvantage and Health Care Spending: A Systematic Review. JAMA Netw Open. 2024 Feb 5;7(2):e2356121. doi: 10.1001/jamanetworkopen.2023.56121. PMCID: PMC10870184.
PMID: 38358740.

Hayes S, Duan KI, Wai TH, Picazo F, Donovan LM, Spece LJ, Plumley R, Slatore CG, Thakur N, Crothers K, Au DH, Feemster LC. Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease Prevalence Among U.S. Veterans. Ann Am Thorac Soc. 2024 Jan 22. doi: 10.1513/AnnalsATS.202308-668RL. Epub ahead of print.
PMID: 38252425.

Bekelman DB, Feser W, Morgan B, Welsh CH, Parsons EC, Paden G, Baron A, Hattler B, McBryde C, Cheng A, Lange AV, Au DH. Nurse and Social Worker Palliative Telecare Team and Quality of Life in Patients With COPD, Heart Failure, or Interstitial Lung Disease: The ADAPT Randomized Clinical Trial. JAMA. 2024 Jan 16;331(3):212-223. doi: 10.1001/jama.2023.24035.
PMID: 38227034

2023

Pearson TA, Vitalis D, Pratt C, Campo R, Armoundas AA, Au D, Beech B, Brazhnik O, Chute CG, Davidson KW, Diez-Roux AV, Fine LJ, Gabriel D, Groenveld P, Hall J, Hamilton AB, Hu H, Ji H, Kind A, Kraus WE, Krumholz H, Mensah GA, Merchant RM, Mozaffarian D, Murray DM, Neumark-Sztainer D, Petersen M, Goff D. The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities. JACC Adv. 2024 Jan;3(1):100759. doi: 10.1016/j.jacadv.2023.100759. Epub 2023 Dec 13. PMCID: PMC10876066.
PMID: 38375059.
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Donovan LM, Keller TL, Stewart NH, Wright J, Spece LJ, Duan KI, Leonhard A, Palen BN, Billings ME, Au DH, Feemster LC. Assessment of Obstructive Sleep Apnea Among Patients With Chronic Obstructive Pulmonary Disease in Primary Care. Chronic Obstr Pulm Dis. 2023 Dec 13. doi: 10.15326/jcopdf.2023.0438. Epub ahead of print.
PMID: 38095613.
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List JM, Palevsky P, Tamang S, Crowley S, Au D, Yarbrough WC, Navathe AS, Kreisler C, Parikh RB, Wang-Rodriguez J, Klutts JS, Conlin P, Pogach L, Meerwijk E, Moy E. Eliminating Algorithmic Racial Bias in Clinical Decision Support Algorithms: Use Cases from the Veterans Health Administration. Health Equity. 2023 Nov 30;7(1):809-816. doi: 10.1089/heq.2023.0037. PMCID: PMC10698768.
PMID: 38076213
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Donovan LM, McDowell JA, Pannick AP, Pai J, Bais AF, Plumley R, Wai TH, Grunwald GK, Josey K, Sayre GG, Helfrich CD, Zeliadt SB, Hoerster KD, Ma J, Au DH. Protocol for a pragmatic trial testing a self-directed lifestyle program targeting weight loss among patients with obstructive sleep apnea (POWER Trial). Contemp Clin Trials. 2023 Nov 5;135:107378. doi: 10.1016/j.cct.2023.107378. Epub ahead of print.
PMID: 37935303
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Duan KI, Donovan LM, Spece LJ, Wong ES, Feemster LC, Bryant AD, Plumley R, Crothers K, Au DH. Inhaler Formulary Change in COPD and the Association with Exacerbations, Health Care Utilization, and Costs. Chronic Obstr Pulm Dis. 2023 Nov 6. doi: 10.15326/jcopdf.2023.0425. Epub ahead of print.
PMID: 37931593.
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Castaneda JM, Hee Wai T, Spece LJ, Duan KI, Leonhard A, Griffith MF, Plumley R, Palen BN, Feemster LC, Au DH, Donovan LM. Risks of Zolpidem among Patients with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2023 Nov 2. doi: 10.1513/AnnalsATS.202307-654OC. Epub ahead of print. PMID: 37916873.
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Au DH, Gleason E, Hunter-Merrill R, Barón AE, Collins M, Ronneberg C, Lv N, Rise P, Wai TH, Plumley R, Wisniewski SR, Sciurba F, Kim DY, Simonelli P, Krishnan JA, Wendt CH, Feemster LC, Criner GJ, Maddipati V, Mohan A, Ma J; Pulmonary Trials Cooperative. Lifestyle Intervention and Excess Weight in COPD: INSIGHT COPD Randomized Clinical Trial. Ann Am Thorac Soc. 2023 Sep 28. doi: 10.1513/AnnalsATS.202305-458OC. Epub ahead of print. PMID: 37769182.
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Donovan LM, Wai T, Spece LJ, Duan KI, Griffith MF, Leonhard A, Plumley R, Hayes SA, Picazo F, Crothers K, Kapur VK, Palen BN, Au DH, Feemster LC. Sleep Testing and Mortality in a Propensity-matched Cohort of Patients with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2023 Aug 14. doi: 10.1513/AnnalsATS.202303-275OC. Epub ahead of print. PMID: 37579136.
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Ives J, Bagchi S, Soo S, Barrow C, Akgün KM, Erlandson KM, Goetz M, Griffith M, Gross R, Hulgan T, Moanna A, Soo Hoo GW, Weintrob A, Wongtrakool C, Adams SV, Sayre G, Helfrich CD, Au DH, Crothers K. Design and methods of a randomized trial testing advancing care for COPD in people living with HIV by implementing evidence-based management through proactive E-consults (ACHIEVE). Contemp Clin Trials. 2023 Jul 20:107303. doi: 10.1016/j.cct.2023.107303. Epub ahead of print.
PMID: 37481201
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Duan KI, Donovan LM, Spece LJ, Feemster LC, Bryant AD, Plumley R, Collins MP, Au DH. Trends and Rural-Urban Differences in the Initial Prescription of Low-Value Inhaled Corticosteroids among US Veterans with COPD. Ann Am Thorac Soc. 2023 Feb 27. doi: 10.1513/AnnalsATS.202205-458OC. Epub ahead of print. PMID: 36867427.
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Stryczek KC, Honsberger M, Ball SL, Barnard JG, Young JP, Felker B, Au DH, Ho PM, Kirsh SR, Sayre GG. VA Outreach Is an Essential Area for Improving Veterans' Health Care Accessibility. Mil Med. 2023 Feb 15:usad019. doi: 10.1093/milmed/usad019. Epub ahead of print.
PMID: 36790439.
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2022

Hoerster KD, Hunter-Merrill R, Nguyen T, Rise P, Barón AE, McDowell J, Donovan LM, Gleason E, Lane A, Plumley R, Schooler M, Schuttner L, Collins M, Au DH, Ma J. Effect of a Remotely Delivered Self-directed Behavioral Intervention on Body Weight and Physical Health Status Among Adults With Obesity: The D-ELITE Randomized Clinical Trial. JAMA. 2022 Dec 13;328(22):2230-2241. doi: 10.1001/jama.2022.21177.
PMID: 36511927.
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Spece LJ, Weppner WG, Weiner BJ, Collins M, Adamson R, Berger DB, Nelson KM, McDowell J, Epler E, Carvalho PG, Woo DM, Donovan LM, Feemster LC, Au DH, Au DH, Sayre G. Primary Care Provider Experience With Proactive E-Consults to Improve COPD Outcomes and Access to Specialty Care. Chronic Obstr Pulm Dis. 2022 Dec 5. doi: 10.15326/jcopdf.2022.0357. Epub ahead of print. PMID: 36472622.
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Duan KI, Birger M, Au DH, Spece LJ, Feemster LC, Dieleman JL. U.S. Health Care Spending on Respiratory Diseases, 1996-2016. Am J Respir Crit Care Med. 2022 Aug 23. doi: 10.1164/rccm.202202-0294OC. Epub ahead of print. PMID: 35997678.
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Reinke LF, Sullivan DR, Slatore C, Dransfield MT, Ruedebusch S, Smith P, Rise PJ, Tartaglione EV, Vig EK, Au DH. A Randomized Trial of a Nurse-Led Palliative Care Intervention for Patients with Newly Diagnosed Lung Cancer. J Palliat Med. 2022 Jun 1. doi: 10.1089/jpm.2022.0008. Epub ahead of print.
PMID: 35649214.
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Au DH, Chang JA, Davidson TA, Donovan LM, Goss CH, Feemster LC, Stapleton RD. Translating Individual Mentorship to Generalizable Action: Lessons Learned From J Randall Curtis. J Pain Symptom Manage. 2022 Jun;63(6):e641-e642. doi: 10.1016/j.jpainsymman.2022.03.014.
PMID: 35595377.
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Duan KI, Wong ES, Liao JM, Sabbatini AK, Au DH. Long-Term Trends in Home Respiratory Medical Equipment among US Medicare Patients, 2013-2019. Am J Respir Crit Care Med. 2022 May 13. doi: 10.1164/rccm.202202-0238LE. Epub ahead of print.
PMID: 35549846.
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Au DH, Collins MP, Berger DB, Carvalho PG, Nelson KM, Reinke LF, Goodman RB, Adamson R, Woo DM, Rise PJ, Coggeshall SS, Plumley RB, Epler EM, Moss BR, McDowell JA, Weppner WG. Health System Approach to Improve COPD Care After Hospital Discharge: Stepped Wedge Clinical Trial. Am J Respir Crit Care Med. 2022 Mar 25. doi: 10.1164/rccm.202107-1707OC. Epub ahead of print.
PMID: 35333140.
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Donovan LM, Parsons EC, McCall CA, He K, Sharma R, Gamache J, Pannick AP, McDowell JA, Pai J, Epler E, Duan KI, Spece LJ, Feemster LC, Kapur VK, Au DH, Palen BN. Impact of mail-based continuous positive airway pressure initiation on treatment usage and effectiveness. Sleep Breath. 2022 Mar 26. doi: 10.1007/s11325-022-02608-z. Epub ahead of print.
PMID: 35347655.
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Donovan LM, Au DH. Sleep Apnea, Obesity, and Readmissions: Real Risks or Residual Confounding? Ann Am Thorac Soc. 2022 Mar;19(3):361-362. doi: 10.1513/AnnalsATS.202111-1304ED.
PMID: 35230227.
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2021

Keller TL, Wright J, Donovan LM, Spece LJ, Duan K, Sulayman N, Dominitz A, Curtis JR, Au DH, Feemster LC. Association of Patient and Primary Care Provider Factors with Outpatient COPD Care Quality. Chronic Obstr Pulm Dis. 2021 Dec 16. doi: 10.15326/jcopdf.2021.0232. Epub ahead of print.
PMID: 34915603.

Donovan LM, Mog AC, Blanchard KN, Magid KH, Syed AS, Kelley LR, Spece LJ, Palen BN, Arfons LM, Kirsh S, Au DH, Sayre GG. Staff Experiences with a Team-based Approach to Sleep Medicine Referrals: A Qualitative Evaluation. Ann Am Thorac Soc. 2021 Nov 17. doi: 10.1513/AnnalsATS.202107-838OC. Epub ahead of print.
PMID: 34788585.

Palen BN, Mattox EA, He K, Beste LA, Borgerding J, Patel S, Au DH, Chang MF, Parsons EC. Impact of Sleep Telementorship in Primary Care: Sleep VA-ECHO (Veterans Affairs-Extension for Community Healthcare Outcomes). Int J Environ Res Public Health. 2021 Sep 21;18(18):9914. doi: 10.3390/ijerph18189914.
PMID: 34574837.

Levy C, Au D, Ozkaynak M. Innovation and Quality Improvement: Safe or Sabotage in Nursing Homes? J Am Med Dir Assoc. 2021 Aug;22(8):1670-1671. doi: 10.1016/j.jamda.2021.06.026.
PMID: 34334162.

Donovan L, Parsons E, Epler E, McCall C, He K, Sharma R, Duan K, Spece L, Feemster L, Kapur V, Au D, Palen B. 677 Impact of Remote Continuous Positive Airway Pressure Set-up on Treatment Usage and Effectiveness. Sleep. 2021 May 3;44(Suppl2):A264–A265.
doi:10.1093/sleep/zsab072.675.

Donovan LM, Mog AC, Blanchard KN, Magid KH, Syed AS, Kelley LR, Palen BN, Parsons EC, McCall CC, Thompson W, Charlton M, Spece LJ, Kirsh S, Au DH, Sayre GG. Patient experiences with telehealth in sleep medicine: a qualitative evaluation. J Clin Sleep Med. 2021 Mar 23. doi: 10.5664/jcsm.9266. Epub ahead of print.
PMID: 33755010.

Marshall V, Stryczek KC, Haverhals L, Young J, Au DH, Ho PM, Kaboli PJ, Kirsh S, Sayre G. The Focus They Deserve: Improving Women Veterans' Health Care Access. Womens Health Issues. 2021 Feb 10:S1049-3867(20)30157-2. doi: 10.1016/j.whi.2020.12.011. Epub ahead of print.
PMID: 33582001.

Prabhu KM, Don C, Sayre GG, Kearney KE, Hira RS, Waldo SW, Rao SV, Au DH, Doll JA. Interventional Cardiologists' Perceptions of Percutaneous Coronary Intervention Quality Measurement and Feedback. Am Heart J. 2021 Feb 7:S0002-8703(21)00032-6. doi: 10.1016/j.ahj.2021.01.019. Epub ahead of print.
PMID: 33567319.

Whittington MD, Ho PM, Kirsh SR, Kenney RR, Todd-Stenberg J, Au DH, Simonetti J. Cost savings associated with electronic specialty consultations. Am J Manag Care. 2021 Jan 1;27(1):e16-e23. doi: 10.37765/ajmc.2021.88579.
PMID: 33471464.

Donovan LM, PalenBN, Fernandes LA, Whittington MD, Feser WJ, Blankenhorn R, Gunzburger E,Grunwald GK, Gamache J, Liao JM, Kirsh S, Au DH. The Referral Coordination Team: A Redesign of Specialty Care to Enhance Service Delivery and Value in Sleep Medicine. NEJM Catalyst Innovations in Care Delivery Vol. 2 No. 2 February 2021.
DOI:https://doi.org/10.1056/CAT.20.0403.

2020

Donovan LM, Palen BN, Syed A, Blankenhorn R, Blanchard K, Feser WJ, Magid K, Gamache J, Spece LJ, Feemster LC, Fernandes L, Kirsh S, Au DH. Nurse-led triage of new sleep referrals is associated with lower risk of potentially contraindicated sleep testing: a retrospective cohort study. BMJ Qual Saf. 2020 Dec 22:bmjqs-2020-011817. doi: 10.1136/bmjqs-2020-011817. Epub ahead of print.
PMID: 33443226.

Moldestad M, Stryczek KC, Haverhals L, Kenney R, Lee M, Ball S, Au D, Kirsh S, Sayre G, Young J. Competing Demands: Scheduling Challenges in Being Veteran-centric in the Setting of Health System Initiatives to Improve Access. Mil Med. 2020 Dec 8:usaa520. doi: 10.1093/milmed/usaa520. Epub ahead of print.
PMID: 33289838.

Griffith MF, Chen HP, Bekelman DB, Feemster LC, Spece LJ, Donovan LM, Au DH, Carey EP. Comorbid Anxiety and Depression, Though Underdiagnosed, Are Not Associated with High Rates of Low-Value Care in Patients with COPD. Ann Am Thorac Soc. 2020 Dec 11. doi: 10.1513/AnnalsATS.201912-877OC. Epub ahead of print.
PMID: 33306930.

Duan KI, Spece LJ, Wong ES, Feemster LC, Donovan LM, Griffith MF, Keller TL, Bryant AD, Au DH. Low-value Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease and the Association with Health Care Utilization and Costs. Ann Am Thorac Soc. 2020 Dec 8. doi: 10.1513/AnnalsATS.202009-1128OC. Epub ahead of print.
PMID: 33290180.

Spece LJ, Epler EM, Duan K, Donovan LM, Griffith MF, LaBedz S, Thakur N, Wiener RS, Krishnan JA, Au DH, Feemster LC. Reassessment of Home Oxygen Prescription after Hospitalization for COPD: A Potential Target for De-implementation. Ann Am Thorac Soc. 2020 Oct 19. doi: 10.1513/AnnalsATS.202004-364OC. Epub ahead of print.
PMID: 33075243.

Parikh TJ, Stryczek KC, Gillespie C, Sayre GG, Feemster L, Udris E, Majerczyk B, Rinne ST, Wiener RS, Au DH, Helfrich CD. Provider anticipation and experience of patient reaction when deprescribing guideline discordant inhaled corticosteroids. PLoS One. 2020 Sep 17;15(9):e0238511. doi: 10.1371/journal.pone.0238511. PMC7498097.
PMID: 32941462.

Harhay MO, Au DH, Dell SD, Gould MK, Redline S, Ryerson CJ, Cooke CR. Methodologic Guidance and Expectations for the Development and Reporting of Prediction Models and Causal Inference Studies. Ann Am Thorac Soc. 2020 Jun;17(6):679-682. doi: 10.1513/AnnalsATS.202002-141ED. PMC7258412.
PMID: 32275840.

Hoerster KD, Collins MP, Au DH, Lane A, Epler E, McDowell J, Barón AE, Rise P, Plumley R, Nguyen T, Schooler M, Schuttner L, Ma J. Testing a self-directed lifestyle intervention among veterans: The D-ELITE pragmatic clinical trial. Contemp Clin Trials. 2020 Aug;95:106045. doi: 10.1016/j.cct.2020.106045. Epub 2020 May 28. PMC7253950.
PMID: 32473403.

Leitao Filho FS, Mattman A, Schellenberg R, Criner GJ, Woodruff P, Lazarus SC, Albert RK, Connett J, Han MK, Gay SE, Martinez FJ, Fuhlbrigge AL, Stoller JK, MacIntyre NR, Casaburi R, Diaz P, Panos RJ, Cooper JA Jr, Bailey WC, LaFon DC, Sciurba FC, Kanner RE, Yusen RD, Au DH, Pike KC, Fan VS, Leung JM, Man SP, Aaron SD, Reed RM, Sin DD. Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis. Chest. 2020 Oct;158(4):1420-1430. doi: 10.1016/j.chest.2020.04.058. Epub 2020 May 19.
PMID: 32439504.

Ball S, Stryczek K, Stevenson L, Hearns R, Au DH, Ho PM, Aron DC. A Qualitative Evaluation of the Pain Management VA-ECHO Program Using the RE-AIM Framework: The Participant's Perspective. Front Public Health. 2020 May 15;8:169. doi: 10.3389/fpubh.2020.00169. eCollection 2020.PMID:
PMID: 32500053.

Spece LJ, Donovan LM, Griffith MF, Keller T, Feemster LC, Smith NL, Au DH. Initiating Low-Value Inhaled Corticosteroids in an Inception Cohort with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2020 May;17(5):589-595. doi: 10.1513/AnnalsATS.201911-854OC.PMID:
PMID: 31899652.

Nici L, Mammen MJ, Charbek E, Alexander PE, Au DH, Boyd CM, Criner GJ, Donaldson GC, Dreher M, Fan VS, Gershon AS, Han MK, Krishnan JA, Martinez FJ, Meek PM, Morgan M, Polkey MI, Puhan MA, Sadatsafavi M, Sin DD, Washko GR, Wedzicha JA, Aaron SD. Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2020 May 1;201(9):e56-e69. doi: 10.1164/rccm.202003-0625ST. Erratum in: Am J Respir Crit Care Med. 2020 Sep 15;202(6):910. PMC7193862.
PMID: 32283960.

Keller T, Spece LJ, Donovan LM, Udris E, Coggeshall SS, Griffith M, Bryant AD, Casaburi R, Cooper JA Jr, Criner GJ, Diaz PT, Fuhlbrigge AL, Gay SE, Kanner RE, Martinez FJ, Panos RJ, Shade D, Sternberg A, Stibolt T, Stoller JK, Tonascia J, Wise R, Yusen RD, Au DH, Feemster LC. Association of Guideline-Recommended COPD Inhaler Regimens With Mortality, Respiratory Exacerbations, and Quality of Life: A Secondary Analysis of the Long-Term Oxygen Treatment Trial. Chest. 2020 Aug;158(2):529-538. doi: 10.1016/j.chest.2020.02.073. Epub 2020 Apr 9. PMC7417382.
PMID: 32278779.

Gamble-George JC, Longenecker CT, Webel AR, Au DH, Brown AF, Bosworth H, Crothers K, Cunningham WE, Fiscella KA, Hamilton AB, Helfrich CD, Ladapo JA, Luque A, Tobin JN, Wyatt GE; Implementation Research to Develop Interventions for People Living with HIV (PRECluDE) Consortium. ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combating chronic disease comorbidities in HIV populations through implementation research. Prog Cardiovasc Dis. 2020 Mar-Apr;63(2):79-91. doi: 10.1016/j.pcad.2020.03.006. Epub 2020 Mar 19. PMC7237329.
PMID: 32199901.

Donovan LM, Fernandes LA, Williams KM, Parsons EC, O'Hearn DJ, He K, McCall CA, Johnson KA, Kennedy MW, Syed AS, Thompson WH, Spece LJ, Feemster LC, Kirsh S, Au DH, Palen BN. Agreement of sleep specialists with registered nurses' sleep study orders in supervised clinical practice. J Clin Sleep Med. 2020 Feb 15;16(2):279-283. doi: 10.5664/jcsm.8182. Epub 2020 Jan 13. PMC7053017.
PMID: 31992435.

2019

Griffith MF, Feemster LC, Zeliadt SB, Donovan LM, Spece LJ, Udris EM, Au DH. Overuse and Misuse of Inhaled Corticosteroids Among Veterans with COPD: a Cross-sectional Study Evaluating Targets for De-implementation. J Gen Intern Med. 2020 Mar;35(3):679-686. doi: 10.1007/s11606-019-05461-1. Epub 2019 Nov 11. PMC7080925.
PMID: 31713043.

Stryczek K, Lea C, Gillespie C, Sayre G, Wanner S, Rinne ST, Wiener RS, Feemster L, Udris E, Au DH, Helfrich CD. De-implementing Inhaled Corticosteroids to Improve Care and Safety in COPD Treatment: Primary Care Providers' Perspectives. J Gen Intern Med. 2020 Jan;35(1):51-56. doi: 10.1007/s11606-019-05193-2. Epub 2019 Aug 8. PMC6957635.
PMID: 31396814.

Donovan LM, Coggeshall SS, Spece LJ, Griffith MF, Palen BN, Parsons EC, Todd-Stenberg JA, Glorioso TJ, Carey EP, Feemster LC, Zeliadt SB, Kirsh S, Au DH. Use of In-Laboratory Sleep Studies in the Veterans Health Administration and Community Care. Am J Respir Crit Care Med. 2019 Sep 15;200(6):779-782. doi: 10.1164/rccm.201902-0313LE. PMC7330508
PMID: 31206308.

Donovan LM, Malte CA, Spece LJ, Griffith MF, Feemster LC, Zeliadt SB, Au DH, Hawkins EJ. Center Predictors of Long-Term Benzodiazepine Use in Chronic Obstructive Pulmonary Disease and Post-traumatic Stress Disorder. Ann Am Thorac Soc. 2019 Sep;16(9):1151-1157. doi: 10.1513/AnnalsATS.201901-048OC. PMC6812159
PMID: 31113231.

Graney BA, Au DH, Barón AE, Cheng A, Combs SA, Glorioso TJ, Paden G, Parsons EC, Rabin BA, Ritzwoller DP, Stonecipher JJ, Turvey C, Welsh CH, Bekelman DB. Advancing Symptom Alleviation with Palliative Treatment (ADAPT) trial to improve quality of life: a study protocol for a randomized clinical trial. Trials. 2019 Jun 13;20(1):355. doi: 10.1186/s13063-019-3417-1. PMC6567600
PMID: 31196156.

Luo G, Stone BL, Koebnick C, He S, Au DH, Sheng X, Murtaugh MA, Sward KA, Schatz M, Zeiger RS, Davidson GH, Nkoy FL. Using Temporal Features to Provide Data-Driven Clinical Early Warnings for Chronic Obstructive Pulmonary Disease and Asthma Care Management: Protocol for a Secondary Analysis. JMIR Res Protoc. 2019 Jun 6;8(6):e13783. doi: 10.2196/13783. PMC6592592
PMID: 31199308.

Griffith MF, Feemster LC, Donovan LM, Spece LJ, Krishnan JA, Lindenauer PK, McBurnie MA, Mularski RA, Au DH. Poor Metered-Dose Inhaler Technique Is Associated with Overuse of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2019 Jun;16(6):765-768. doi: 10.1513/AnnalsATS.201812-889RL. PMC6543465
PMID: 30763114.

Reinke LF, Vig EK, Tartaglione EV, Rise P, Au DH. Symptom Burden and Palliative Care Needs Among High-Risk Veterans With Multimorbidity. J Pain Symptom Manage. 2019 May;57(5):880-889. doi: 10.1016/j.jpainsymman.2019.02.011. Epub 2019 Feb 19.
PMID: 30794938.

Lederer DJ, Au DH, Cooke CR, Dell SD, Gould MK, Redline S, Kotloff RM. AnnalsATS: New Developments and Advice for Authors. Ann Am Thorac Soc. 2019 May;16(5):540-542. doi: 10.1513/AnnalsATS.201902-143ED.
PMID: 31042094.

Stefan MS, Shieh MS, Spitzer KA, Pekow PS, Krishnan JA, Au DH, Lindenauer PK. Association of Antibiotic Treatment With Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated With Systemic Corticosteroids. JAMA Intern Med. 2019 Mar 1;179(3):333-339. doi: 10.1001/jamainternmed.2018.5394. PMC6439702
PMID: 30688986.

Helfrich CD, Hartmann CW, Parikh TJ, Au DH. Promoting Health Equity through De-Implementation Research. Ethn Dis. 2019 Feb 21;29(Suppl 1):93-96. doi: 10.18865/ed.29.S1.93. eCollection 2019. PMC6428172
PMID: 30906155.

Moy ML, Harrington KF, Sternberg AL, Krishnan JA, Albert RK, Au DH, Casaburi R, Criner GJ, Diaz P, Kanner RE, Panos RJ, Stibolt T, Stoller JK, Tonascia J, Yusen RD, Tan AM, Fuhlbrigge AL; LOTT Research Group. Characteristics at the time of oxygen initiation associated with its adherence: Findings from the COPD Long-term Oxygen Treatment Trial. Respir Med. 2019 Mar;149:52-58. doi: 10.1016/j.rmed.2019.02.004. Epub 2019 Feb 13. PMC6424633
PMID: 30803886.

Doll JA, Jones WS, Lokhnygina Y, Culpepper S, Parks RL, Calhoun C, Au DH, Patel MR. PREPARED Study: A Study of Shared Decision-Making for Coronary Artery Disease. Circ Cardiovasc Qual Outcomes. 2019 Feb;12(2):e005244. doi: 10.1161/CIRCOUTCOMES.118.005244.
PMID: 30764651.

Press VG, Au DH, Bourbeau J, Dransfield MT, Gershon AS, Krishnan JA, Mularski RA, Sciurba FC, Sullivan J, Feemster LC. Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 Feb;16(2):161-170. doi: 10.1513/AnnalsATS.201811-755WS. PMC6812156
PMID: 30707066.

Rinne ST, Wiener RS, Chen Y, Rise P, Udris E, Feemster LC, Au DH. Reply to Kardos: Extent of Overuse of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2019 Jan 15;199(2):249-250. doi: 10.1164/rccm.201809-1732LE.
PMID: 30278144.

Donovan LM, Feemster LC, Udris EM, Griffith MF, Spece LJ, Palen BN, He K, Parthasarathy S, Strohl KP, Kapur VK, Au DH. Poor Outcomes Among Patients With Chronic Obstructive Pulmonary Disease With Higher Risk for Undiagnosed Obstructive Sleep Apnea in the LOTT Cohort. J Clin Sleep Med. 2019 Jan 15;15(1):71-77. doi: 10.5664/jcsm.7574. PMC6329538
PMID: 30621828.

Donovan LM, Malte CA, Spece LJ, Griffith MF, Feemster LC, Engelberg RA, Au DH, Hawkins EJ. Risks of Benzodiazepines in Chronic Obstructive Pulmonary Disease with Comorbid Posttraumatic Stress Disorder. Ann Am Thorac Soc. 2019 Jan;16(1):82-90. doi: 10.1513/AnnalsATS.201802-145OC. PMC6344455
PMID: 30309243.

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