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Seattle-Denver Center of Innovation (COIN)

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COIN Investigators & Staff

COIN Investigators

 

Kristina A Crothers, MD
Title: Professor, Medicine and Pulmonary, Critical Care and Sleep Medicine, University of Washington
Contact: Kristina.Crothers@va.gov
Location: Seattle
University of Washington webpage
See Dr. Crothers' Dimensions profile that includes: publications, grants, datasets, patents and clinical trials

The following images visualize Dr. Crothers' work. The word cloud is drawn from publication titles. The research collaboration map shows research relationships (click the image to enlarge):

Dr. Crothers' publication titles indicate his primary work is care of Veterans
Word cloud from pub titles
Dr. Crothers' collaborations are primarily from the University of Washington
Research collaboration map
The following research fields have been used to summarize Dr. Crothers' publications and grants. The categories are based on 264 publications and 10 grants.
Publications Grants
Clinical Research Clinical Research
Lung Lung
Infectious Diseases HIV/AIDS
HIV/AIDS Infectious Diseases
Prevention Prevention
Cancer Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Tobacco
Tobacco Tobacco Smoke and Health
Tobacco Smoke and Health Aging
Pneumonia & Influenza Health Services

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Recent Publications

 

2022

 

Bade B, Gwin M, Triplette M, Wiener RS, Crothers K. Comorbidity and life expectancy in shared decision making for lung cancer screening. Semin Oncol. 2022 Jul 21:S0093-7754(22)00057-4. doi: 10.1053/j.seminoncol.2022.07.003. Epub ahead of print. PMID: 35940959
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Yee N, Mann BA, Crothers KA, Albert TJ. 52-year-old man • hematemesis • history of cirrhosis • persistent fevers • Dx? J Fam Pract. 2022 Apr;71(3):E17-E19. doi: 10.12788/jfp.0385. PMID: 35561241
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Zifodya JS, Crothers K. Tuberculosis, Chronic Obstructive Lung Disease, and Lung Cancer: The Holey Upper Lobe Trinity? Ann Am Thorac Soc. 2022 Apr;19(4):540-542. doi: 10.1513/AnnalsATS.202201-009ED. PMID: 35363131
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Luu B, Ruderman S, Nance R, Delaney JAC, Ma J, Hahn A, Heckbert SR, Budoff MJ, Crothers K, Mathews WC, Christopolous K, Hunt PW, Eron J, Moore R, Keruly J, Lober WB, Burkholder GA, Willig A, Chander G, McCaul ME, Cropsey K, O'Cleirigh C, Peter I, Feinstein M, Tsui JI, Lindstroem S, Saag M, Kitahata MM, Crane HM, Drumright LN, Whitney BM. Tobacco smoking and binge alcohol use are associated with incident venous thromboembolism in an HIV cohort. HIV Med. 2022 Mar 28. doi: 10.1111/hiv.13309. Epub ahead of print. PMID: 35343038
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Holman A, Kross E, Crothers K, Cole A, Wernli K, Triplette M. Patient Perspectives on Longitudinal Adherence to Lung Cancer Screening. Chest. 2022 Feb 8:S0012-3692(22)00223-9. doi: 10.1016/j.chest.2022.01.054. Epub ahead of print. PMID: 35149081
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2021

 

Crothers K, DeFaccio R, Tate J, Alba PR, Goetz MB, Jones B, King JT Jr, Marconi V, Ohl ME, Rentsch CT, Rodriguez-Barradas MC, Shahrir S, Justice AC, Akgün KM; Veterans Aging Cohort Study Clinical COVID-19 Working Group. Dexamethasone in hospitalised coronavirus-19 patients not on intensive respiratory support. Eur Respir J. 2021 Nov 25:2102532. doi: 10.1183/13993003.02532-2021. Epub ahead of print. PMID: 34824060

Crothers K, Schnapp L. World AIDS Day: 40 Years of an Evolving Pulmonary Landscape. Am J Physiol Lung Cell Mol Physiol. 2021 Nov 10. doi: 10.1152/ajplung.00457.2021. Epub ahead of print. PMID: 34755570

McClure JB, Catz SL, Chalal C, Ciuffetelli R, Coggeshall S, DeFaccio RJ, Fleehart S, Heffner JL, Thompson E, Williams EC, Crothers K. Design and methods of a randomized trial testing the novel Wellness Intervention for Smokers Living with HIV (WISH). Contemp Clin Trials. 2021 Nov;110:106486. doi: 10.1016/j.cct.2021.106486. Epub 2021 Oct 27. PMID: 34776121

Triplette M, Wenger DS, Shahrir S, Kross EK, Kava C, Phipps A, Hawes SE, Cole A, Snidarich M, Crothers K. Patient Identification of Lung Cancer Screening Follow-up Recommendations and the Association with Adherence. Ann Am Thorac Soc. 2021 Nov 2. doi: 10.1513/AnnalsATS.202107-887OC. Epub ahead of print. PMID: 34727513

Zifodya JS, Triplette M, Shahrir S, Attia EF, Akgun KM, Soo Hoo GW, Rodriguez-Barradas MC, Wongtrakool C, Huang L, Crothers K. A cross-sectional analysis of diagnosis and management of chronic obstructive pulmonary disease in people living with HIV: Opportunities for improvement. Medicine (Baltimore). 2021 Sep 17;100(37):e27124. doi: 10.1097/MD.0000000000027124. PMCID: PMC8448060. PMID: 34664836

Leapman MS, Stone K, Wadia R, Park LS, Gibert CL, Goetz MB, Bedimo R, Rodriguez-Barradas M, Shebl F, Justice AC, Brown ST, Crothers K, Sigel KM. Prostate Cancer Screening and Incidence Among Aging Persons Living with HIV. J Urol. 2021 Sep 24:101097JU0000000000002249. doi: 10.1097/JU.0000000000002249. Epub ahead of print. PMID: 34555924

Zifodya JS, Triplette M, Shahrir S, Attia EF, Akgun KM, Soo Hoo GW, Rodriguez-Barradas MC, Wongtrakool C, Huang L, Crothers K. A cross-sectional analysis of diagnosis and management of chronic obstructive pulmonary disease in people living with HIV: Opportunities for improvement. Medicine (Baltimore). 2021 Sep 17;100(37):e27124. doi: 10.1097/MD.0000000000027124. PMCID: PMC8448060

Makinson A, Park LS, Stone K, Tate J, Rodriguez-Barradas MC, Brown ST, Wadia R, Crothers K, Bedimo R, Goetz MB, Shebl F, Reynes J, Moing VL, Sigel KM. Risks of Opportunistic Infections in People With Human Immunodeficiency Virus With Cancers Treated With Chemotherapy. Open Forum Infect Dis. 2021 Jul 19;8(8):ofab389. doi: 10.1093/ofid/ofab389. PMCID: PMC8391784. PMID: 34458394

Jan AK, Moore JV, Wang RJ, Mcging M, Farr CK, Moisi D, Hartman-Filson M, Kerruish R, Jeon D, Lewis E, Crothers K, Lederman MM, Hunt PW, Huang L. Markers of inflammation and immune activation are associated with lung function in a multi-center cohort of persons with HIV. AIDS. 2021 Jun 1;35(7):1031-1040. doi: 10.1097/QAD.0000000000002846. PMCID: PMC8102352. PMID: 33635847

Singhvi DG, Nouraie M, Kessinger C, McMahon DK, Weinman R, Crothers K, Huang L, Bon J, Morris A, Merlin J. Brief Report: Association Between Pain, Pulmonary Function, and Respiratory Symptoms in People With HIV. J Acquir Immune Defic Syndr. 2021 Aug 15;87(5):1161-1166. doi: 10.1097/QAI.0000000000002696. PMCID: PMC8263479. PMID: 33871410

Duncan MS, Alcorn CW, Freiberg MS, So-Armah K, Patterson OV, DuVall SL, Crothers KA, Re VL 3rd, Butt AA, Lim JK, Kim JW, Tindle HA, Justice AC, Brittain EL. Association between HIV and incident pulmonary hypertension in US Veterans: a retrospective cohort study. Lancet Healthy Longev. 2021 Jul;2(7):e417-e425. doi: 10.1016/s2666-7568(21)00116-1. Epub 2021 Jun 16. PMCID: PMC8294078. PMID: 34296203

Akgün KM, Krishnan S, Butt AA, Gibert CL, Graber CJ, Huang L, Pisani MA, Rodriguez-Barradas MC, Hoo GWS, Justice AC, Crothers K, Tate JP. HIV-infected medical ICU (MICU) survivors without CD4 cell recovery are at increased risk for poor outcomes regardless of viral suppression in a national cohort. AIDS. 2021 Jul 8. doi: 10.1097/QAD.0000000000003019. Epub ahead of print. PMID: 34261095

Ohl ME, Miller DR, Lund BC, Kobayashi T, Richardson Miell K, Beck BF, Alexander B, Crothers K, Vaughan Sarrazin MS. Association of Remdesivir Treatment With Survival and Length of Hospital Stay Among US Veterans Hospitalized With COVID-19. JAMA Netw Open. 2021 Jul 1;4(7):e2114741. doi: 10.1001/jamanetworkopen.2021.14741. PMCID: PMC8283561. PMID: 34264329

Zifodya JS, Temu TM, Masyuko SJ, Nyale G, Kinuthia J, Page ST, LaCourse SM, Kolls J, Farquhar C, Crothers K. HIV, Pulmonary Infections, and Risk of Chronic Lung Disease among Kenyan Adults. Ann Am Thorac Soc. 2021 Jul 8. doi: 10.1513/AnnalsATS.202103-251RL. Epub ahead of print. PMID: 34237231

O'Hare AM, Berry K, Fan VS, Crothers K, Eastment MC, Dominitz JA, Shah JA, Green P, Locke E, Ioannou GN. Age differences in the association of comorbid burden with adverse outcomes in SARS-CoV-2. BMC Geriatr. 2021 Jul 6;21(1):415. doi: 10.1186/s12877-021-02340-5. PMCID: PMC8258273. PMID: 34229623.

Dela Cruz CS, Evans SE, Restrepo MI, Dean N, Torres A, Amara-Elori I, Awasthi S, Caler E, Cao B, Chalmers JD, Chastre J, Cohen TS, Cohen AH, Crothers K, Di YP, Egan ME, Feldman C, Gautam S, Halstead ES, Herold S, Jones BE, Luna C, Niederman MS, Mendez R, Menendez R, Mizgerd JP, Nusrat R, Ramirez J, Shindo Y, Waterer G, Yeligar SM, Wunderink RG. Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2021 Jul;18(7):1087-1097. doi: 10.1513/AnnalsATS.202102-209ST. PMID: 34242148

Chichetto NE, Kundu S, Freiberg MS, Koethe JR, Butt AA, Crystal S, So-Armah KA, Cook RL, Braithwaite RS, Justice AC, Fiellin DA, Khan M, Bryant KJ, Gaither JR, Barve SS, Crothers K, Bedimo RJ, Warner A, Tindle HA; Veterans Aging Cohort Study. Association of Syndemic Unhealthy Alcohol Use, Smoking, and Depressive Symptoms on Incident Cardiovascular Disease among Veterans With and Without HIV-Infection. AIDS Behav. 2021 Jun 8. doi: 10.1007/s10461-021-03327-4. Epub ahead of print. PMID: 34101074

Ioannou GN, O'Hare AM, Berry K, Fan VS, Crothers K, Eastment MC, Locke E, Green P, Shah JA, Dominitz JA. Trends over time in the risk of adverse outcomes among patients with SARS-CoV-2 infection. Clin Infect Dis. 2021 May 11:ciab419. doi: 10.1093/cid/ciab419. Epub ahead of print. PMID: 33973000

Evans SE, Jennerich AL, Azar MM, Cao B, Crothers K, Dickson RP, Herold S, Jain S, Madhavan A, Metersky ML, Myers LC, Oren E, Restrepo MI, Semret M, Sheshadri A, Wunderink RG, Dela Cruz CS. Nucleic Acid-based Testing for Noninfluenza Viral Pathogens in Adults with Suspected Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2021 May 1;203(9):1070-1087. doi: 10.1164/rccm.202102-0498ST. PMID: 33929301

Triplette M, Crothers K. Reply: Early Adherence to Lung Cancer Screening. Ann Am Thorac Soc. 2021 Apr;18(4):734. doi: 10.1513/AnnalsATS.202101-061LE. PMCID: PMC8009006. PMID: 33507854

Shen J, Crothers K, Kross EK, Petersen K, Melzer AC, Triplette M. Provision of Smoking Cessation Resources in the Context of In-Person Shared Decision-Making for Lung Cancer Screening. Chest. 2021 Aug;160(2):765-775. doi: 10.1016/j.chest.2021.03.016. Epub 2021 Mar 18. PMID: 33745990

Sigel K, Kong CY, Rehmani S, Bates S, Gould M, Stone K, Kale M, Park YH, Crothers K, Bhora F, Wisnivesky J. Optimal treatment strategies for stage I non-small cell lung cancer in veterans with pulmonary and cardiac comorbidities. PLoS One. 2021 Mar 18;16(3):e0248067. doi: 10.1371/journal.pone.0248067. PMCID: PMC7971489. PMID: 33735217

Schnoll R, Bernstein SL, Kaufman A, Gross R, Catz SL, Cioe PA, Hitsman B, Marhefka SL, Pacek LR, Vidrine DJ, Vilardaga R, Edelman EJ, McClure JB, Ashare R, Lockhart E, Crothers K. COVID-19 Challenges Confronted by Smoking Cessation Clinical Trials for People Living with HIV: The Experience of Grantees of the United States National Cancer Institute. Nicotine Tob Res. 2021 Feb 28:ntab035. doi: 10.1093/ntr/ntab035. Epub ahead of print. PMCID: PMC7989188. PMID: 33657227

Ehteshami-Afshar S, Crothers K, Rodwin B, Bade B, Brandt C, Akgün KM. Does pulmonary subspecialty referral from primary care affect the adherence to vaccination recommendations in COPD patients? Respir Res. 2021 Feb 12;22(1):50. doi: 10.1186/s12931-021-01639-6. Erratum in: Respir Res. 2021 Mar 15;22(1):82. PMCID: PMC7880521. PMID: 33579277

Bedimo RJ, Park LS, Shebl FM, Sigel K, Rentsch CT, Crothers K, Rodriguez-Barradas MC, Goetz MB, Butt AA, Brown ST, Gibert C, Justice AC, Tate JP. Statin exposure and risk of cancer in people with and without HIV infection. AIDS. 2021 Feb 2;35(2):325-334. doi: 10.1097/QAD.0000000000002748. PMCID: PMC7775280. PMID: 33181533

2020

 

Zifodya JS, Duncan MS, So-Armah KA, Attia EF, Akgün KM, Rodriguez-Barradas MC, Marconi VC, Budoff MJ, Bedimo RJ, Alcorn CW, Soo Hoo GW, Butt AA, Kim JW, Sico JJ, Tindle HA, Huang L, Tate JP, Justice AC, Freiberg MS, Crothers K. Community-Acquired Pneumonia and Risk of Cardiovascular Events in People Living With HIV. J Am Heart Assoc. 2020 Dec;9(23):e017645. doi: 10.1161/JAHA.120.017645. Epub 2020 Nov 23. PMCID: PMC7763776. PMID: 33222591

Eastment MC, Berry K, Locke E, Green P, O'Hare A, Crothers K, Dominitz J, Fan VS, Shah JA, Ioannou GN. Body mass index (BMI) and outcomes of SARS-CoV-2 among US veterans. Obesity (Silver Spring). 2020 Dec 18. doi: 10.1002/oby.23111. Epub ahead of print. PMID: 33336934

Ioannou GN, Liang PS, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Eastment MC, Fan VS, Dominitz JA. Cirrhosis and SARS-CoV-2 infection in US Veterans: risk of infection, hospitalization, ventilation and mortality. Hepatology. 2020 Nov 21. doi: 10.1002/hep.31649. Epub ahead of print. PMID: 33219546

Fan VS, Dominitz JA, Eastment MC, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Ioannou GN. Risk Factors for testing positive for SARS-CoV-2 in a national US healthcare system. Clin Infect Dis. 2020 Oct 27:ciaa1624. doi: 10.1093/cid/ciaa1624. Epub ahead of print. PMCID: PMC7665412. PMID: 33105485

Wenger DS, Triplette M, Shahrir S, Akgun KM, Wongtrakool C, Brown ST, Kim JW, Soo Hoo GW, Rodriguez-Barradas MC, Huang L, Feemster LC, Zifodya J, Crothers K. Associations of marijuana with markers of chronic lung disease in people living with HIV. HIV Med. 2020 Oct 6. doi: 10.1111/hiv.12966. Epub ahead of print. PMID: 33022830

Zola CE, Duncan MS, So-Armah K, Crothers KA, Butt AA, Gibert CL, Kim JWW, Lim JK, Re VL 3rd, Tindle HA, Freiberg MS, Brittain EL. HIV- and HCV-specific markers and echocardiographic pulmonary artery systolic pressure among United States veterans. Sci Rep. 2020 Oct 30;10(1):18729. doi: 10.1038/s41598-020-75290-4. PMCID: PMC7599329. PMID: 33127959

Bai C, Chotirmall SH, Rello J, Alba GA, Ginns LC, Krishnan JA, Rogers R, Bendstrup E, Burgel PR, Chalmers JD, Chua A, Crothers KA, Duggal A, Kim YW, Laffey JG, Luna CM, Niederman MS, Raghu G, Ramirez JA, Riera J, Roca O, Tamae-Kakazu M, Torres A, Watkins RR, Barrecheguren M, Belliato M, Chami HA, Chen R, Cortes-Puentes GA, Delacruz C, Hayes MM, Heunks LMA, Holets SR, Hough CL, Jagpal S, Jeon K, Johkoh T, Lee MM, Liebler J, McElvaney GN, Moskowitz A, Oeckler RA, Ojanguren I, O'Regan A, Pletz MW, Rhee CK, Schultz MJ, Storti E, Strange C, Thomson CC, Torriani FJ, Wang X, Wuyts W, Xu T, Yang D, Zhang Z, Wilson KC. Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020). Eur Respir Rev. 2020 Oct 5;29(157):200287. doi: 10.1183/16000617.0287-2020. PMCID: PMC7537943. PMID: 33020069

Ramirez JA, Musher DM, Evans SE, Dela Cruz C, Crothers KA, Hage CA, Aliberti S, Anzueto A, Arancibia F, Arnold F, Azoulay E, Blasi F, Bordon J, Burdette S, Cao B, Cavallazzi R, Chalmers J, Charles P, Chastre J, Claessens YE, Dean N, Duval X, Fartoukh M, Feldman C, File T, Froes F, Furmanek S, Gnoni M, Lopardo G, Luna C, Maruyama T, Menendez R, Metersky M, Mildvan D, Mortensen E, Niederman MS, Pletz M, Rello J, Restrepo MI, Shindo Y, Torres A, Waterer G, Webb B, Welte T, Witzenrath M, Wunderink R. Treatment of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies. Chest. 2020 Nov;158(5):1896-1911. doi: 10.1016/j.chest.2020.05.598. Epub 2020 Jun 16. PMCID: PMC7297164. PMID: 32561442

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Grants & Funding

 

Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs (LAUREL Study)

NIH website: https://reporter.nih.gov/project-details/10187862

Improving the Reach and Effectiveness of Smoking Cessation Services Targeted to Veterans Living with HIV

NIH website: https://reporter.nih.gov/project-details/10020915

AdvanCing High quality COPD care for people with immune dysfunction by implementing Evidence-based management through proactive E-consults (ACHIEVE)

NIH website: https://reporter.nih.gov/project-details/9966024

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Awards, Honors

 

2021 VA Hospital & Specialty Medicine, Practitioner Lead in Quality & Safety (PLQS) Award for the VISN 20 Centralized Lung Cancer Screening Project, Fiscal Year 2021

2017 University of Washington Department of Medicine Mentoring Award for Physician-Scientists