COIN Investigators & Staff
COIN Affiliate Investigator
-
Jason A. Dominitz, MD, MHS
- Title:Seattle-Denver COIN Affiliate
Executive Director for Gastroenterology and Hepatology, Department of Veterans Affairs
Professor, Division of Gastroenterology, Department of Medicine, University of Washington - Contact: jason.dominitz@va.gov
- Location: Seattle
- University of Washington webpage
- See Dr. Dominitz's Dimensions profile that includes: publications, grants, datasets, patents and clinical trials
- Jason Dominitz, MD, MHS is the Executive Director for Gastroenterology and Hepatology in the US Department of Veterans Affairs and Professor of Medicine at the University of Washington. Dr. Dominitz joined the VA Puget Sound in Seattle, Washington in 1997 after completing his residency and gastroenterology fellowship at Duke University, a fellowship in VA Health Systems Research at the Durham VA, and a master’s degree in clinical research from the Duke University School of Medicine.
- Dr. Dominitz has a longstanding interest in colorectal cancer screening and treatment. During his gastroenterology fellowship, he studied patient preferences for colorectal cancer screening and conducted a study of racial differences in colorectal cancer treatment. He has collaborated with local investigators at the University of Washington and with colleagues around the United States on studies of the quality of colonoscopy and of colorectal cancer treatment. Currently, he co-chairs a 16-year randomized, prospective VA cooperative study comparing screening with annual fecal immunochemical tests to screening colonoscopy in 50,000 average risk Veterans (the CONFIRM Study). In 2022, the VA Puget Sound was awarded funding to join the Network of Dedicated Enrollment Sites (NODES) with Dr. Dominitz as the Director of this new program. The Puget Sound NODES will serve to enhance the research enterprise in the Pacific Northwest, including training for junior investigators and support for research enrollment.
- Dr. Dominitz has served as the Executive Director for Gastroenterology and Hepatology since 2011. His work has focused on assuring Veterans’ access to high quality gastroenterology services. He is particularly interested in colonoscopy quality improvement and has led the development of new policies and tools related to this issue. Dr. Dominitz is the VA representative to the National Colorectal Cancer Round Table and is a member of the US Multi-Society Task Force on Colorectal Cancer. He is also an active member of the American Society for Gastrointestinal Endoscopy, currently serving as a member of the Quality in Endoscopy Committee and formerly serving as a counselor on the Governing Board and as chair of the Standards of Practice Committee. He also serves as a member of the Gastroenterology Devices Panel of the FDA Center for Devices and Radiologic Health.
Recent Publications
2024
von Rosenvinge EC, Vela SA, Paine ER, Chang MF, Hanson BJ, Taddei T, Smalley WE, Dunbar KB, Khan NH, Kahng LS, Anwar J, Zing R, Gawron A, Dominitz JA, Baffy G. A Crisis in Scope: Recruitment and Retention Challenges Reported by VA Gastroenterology Section Chiefs. Fed Pract. 2024 Aug;41(8):256-260. doi: 10.12788/fp.0504. Epub 2024 Aug 15. PMID: 39410921; PMCID: PMC11473028.
PMID: 39410921
Minot SS, Li N, Srinivasan H, Ayers JL, Yu M, Koester ST, Stangis MM, Dominitz JA, Halberg RB, Grady WM, Dey N. Colorectal cancer-associated bacteria are broadly distributed in global microbiomes and drivers of precancerous change. Sci Rep. 2024 Oct 9;14(1):23646. doi: 10.1038/s41598-024-70702-1. PMID: 39384807; PMCID: PMC11464690.
PMID: 39384807.
Williams AR, Redding TS, Sullivan BA, Baidya RN, Ear B, Cho K, Ivey KL, Williams CD, Dominitz JA, Lieberman D, Hauser ER. Recalibrating the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO) Environmental Risk Score for Use in US Veterans. Cancer Epidemiol Biomarkers Prev. 2024 Sep 10. doi: 10.1158/1055-9965.EPI-24-0791. Epub ahead of print.
PMID: 39254429.
Drekonja DM, Shaukat A, Huang Y, Zhang JH, Reinink AR, Nugent S, Dominitz JA, Davis-Karim A, Gerding DN, Kyriakides TC. A randomized controlled trial of efficacy and safety of Fecal Microbiota Transplant for preventing recurrent Clostridioides difficile infection. Clin Infect Dis. 2024 Sep 13:ciae467. doi: 10.1093/cid/ciae467. Epub ahead of print.
PMID: 39271107.
Ladabaum U, Mannalithara A, Schoen RE, Dominitz JA, Lieberman D. Reply to Aziz et al. Gastroenterology. 2024 Aug 27:S0016-5085(24)05409-X. doi: 10.1053/j.gastro.2024.08.027. Epub ahead of print.
PMID: 39209125.
Gawron AJ, McKee G, Dominitz JA, Yao Y, Whooley M, Kaltenbach T. VALIDATION OF A NATIONAL PATHOLOGY DATABASE FOR COLONOSCOPY QUALITY REPORTING AND ASSURANCE. Clin Gastroenterol Hepatol. 2024 Aug 27:S1542-3565(24)00787-0. doi: 10.1016/j.cgh.2024.08.017. Epub ahead of print.
PMID: 39209190.
Rex DK, Anderson JC, Butterly LF, Day LW, Dominitz JA, Kaltenbach T, Ladabaum U, Levin TR, Shaukat A, Achkar JP, Farraye FA, Kane SV, Shaheen NJ. Quality indicators for colonoscopy. Gastrointest Endosc. 2024 Sep;100(3):352-381. doi: 10.1016/j.gie.2024.04.2905. Epub 2024 Aug 21.
PMID: 39177519.
Rex DK, Anderson JC, Butterly LF, Day LW, Dominitz JA, Kaltenbach T, Ladabaum U, Levin TR, Shaukat A, Achkar JP, Farraye FA, Kane SV, Shaheen NJ. Quality Indicators for Colonoscopy. Am J Gastroenterol. 2024 Aug 21. doi: 10.14309/ajg.0000000000002972. Epub ahead of print.
PMID: 39167112.
Sullivan BA, Gilles H, Knauf L, Choi SS, Moore J, Dominitz JA. Development and Implementation of a Clinical Decision Support Tool to Improve Adherence to Colonoscopy Follow-Up Guidelines. Gastroenterology. 2024 Aug 8:S0016-5085(24)05304-6. doi: 10.1053/j.gastro.2024.08.004. Epub ahead of print.
PMID: 39127157.
Shapiro JA, Holub JL, Dominitz JA, Sabatino SA, Nadel MR. Colonoscopy Quality Measures and Adherence to Follow-up Guidelines Among Endoscopists Participating in a United States Endoscopy Registry. Gastrointest Endosc. 2024 Aug 5:S0016-5107(24)03404-7. doi: 10.1016/j.gie.2024.07.027. Epub ahead of print.
PMID: 39111394.
Cohen-Mekelburg S, Johnson J, Paine E, Prasad MA, Dominitz JA, Hou J. Assessment of Physician Needs and Access to Inflammatory Bowel Disease Specialty Care Resources in a National Integrated Health System. Dig Dis Sci. 2024 Jul 27. doi: 10.1007/s10620-024-08560-0. Epub ahead of print.
PMID: 39068377.
Brian A. Sullivan, Xuejun Qin, Thomas S. Redding, David Weiss, Julie Upchurch, Kellie J. Sims, Jason A. Dominitz, Anjanette Stone, Belinda Ear, Christina D. Williams, David A. Lieberman, Elizabeth R. Hauser. Colorectal Cancer Polygenic Risk Score Is Associated With Screening Colonoscopy Findings but Not Follow-Up Outcomes. Gastro Hep Advances, Volume 3, Issue 2, 2024, Pages 151-161, ISSN 2772-5723.
DOI: 10.1016/j.gastha.2023.10.001.
Ladabaum U, Mannalithara A, Weng Y, Schoen RE, Dominitz JA, Desai M, Lieberman D. Comparative Effectiveness and Cost-Effectiveness of Colorectal Cancer Screening With Blood-Based Biomarkers (Liquid Biopsy) vs Fecal Tests or Colonoscopy. Gastroenterology. 2024 Mar 21:S0016-5085(24)00293-2. doi: 10.1053/j.gastro.2024.03.011. Epub ahead of print.
PMID: 38552670.
2023
Pokala SK, Williams JL, Holub JL, Calderwood AH, Dominitz JA, Iyer PG, Shaheen NJ, Wani S. SIGNIFICANT REDUCTION IN THE DIAGNOSIS OF BARRETT'S ESOPHAGUS AND RELATED DYSPLASIA DURING THE COVID-19 PANDEMIC. Am J Gastroenterol. 2023 Oct 2. doi: 10.14309/ajg.0000000000002527. Epub ahead of print. PMID: 37782262.
PMID: 37782262.
Deeds S, Schuttner L, Wheat C, Gunnink E, Geyer J, Beste L, Chen A, Dominitz JA, Nelson K, Reddy A. Automated Reminders Enhance Mailed Fecal Immunochemical Test Completion Among Veterans: a Randomized Controlled Trial. J Gen Intern Med. 2023 Sep 20. doi: 10.1007/s11606-023-08409-8. Epub ahead of print.
PMID: 37731137.
Rex DK, Ladabaum U, Anderson JC, Shaukat A, Butterly LF, Dominitz JA, Kaltenbach T, Levin TR, Hassan C. Does Screening Colonoscopy Have a Future in the U.S.? Clin Gastroenterol Hepatol. 2023 Aug 1:S1542-3565(23)00578-5. doi: 10.1016/j.cgh.2023.05.034. Epub ahead of print. PMID: .
PMID: 37536529.
Deeds S, Liu T, Schuttner L, Wheat C, Gunnink E, Geyer J, Beste L, Chen A, Dominitz JA, Nelson K, Reddy A. A Postcard Primer Prior to Mailed Fecal Immunochemical Test Among Veterans: a Randomized Controlled Trial. J Gen Intern Med. 2023 Jun 8:1–7. doi: 10.1007/s11606-023-08248-7. Epub ahead of print. PMCID: PMC10249919.
PMID: 37291363.
Dominitz JA. Key landmarks to be documented and photographed during colonoscopy. Gastrointest Endosc. 2023 Mar 12:S0016-5107(23)00311-5. doi: 10.1016/j.gie.2023.03.011. Epub ahead of print.
PMID: 36918073
Adejumo AC, Yakovchenko V, Morgan TR, Spoutz P, Chia L, Bajaj JS, Chang MF, Dominitz JA, Rogal SS. The road to pandemic recovery: Tracking COVID-19's impact on cirrhosis care and outcomes among 111,558 veterans. Hepatology. 2023 Jan 30. doi: 10.1097/HEP.0000000000000306. Epub ahead of print.
PMID: 36705024
2022
Deeds SA, Moore CB, Gunnink EJ, Wheat CL, Robinson AE, Bomsztyk MD, Geyer JR, Chen A, Godbout RM, Nelson KM, Dominitz JA, Reddy A. Implementation of a mailed faecal immunochemical test programme for colorectal cancer screening among Veterans. BMJ Open Qual. 2022 Nov;11(4):e001927. doi: 10.1136/bmjoq-2022-001927. PMCID: PMC9670919.
PMID: 36384879
Learn more about this publication on Dimensions
Dominitz JA, Robertson DJ. Understanding the Results of a Randomized Trial of Screening Colonoscopy. N Engl J Med. 2022 Oct 9. doi: 10.1056/NEJMe2211595. Epub ahead of print.
PMID: 36214591
Demb J, Liu L, Bustamante R, Dominitz JA, Earles A, Shah SC, Gawron AJ, Martinez ME, Gupta S. COVID-19 Pandemic Had Minimal Impact on Colonoscopy Completion After Colorectal Cancer Red Flag Sign or Symptoms in US Veterans. Dig Dis Sci. 2022 Sep 28:1–10. doi: 10.1007/s10620-022-07685-4. Epub ahead of print. PMCID: PMC9516530.
PMID: 36169748
Adams MA, Kerr EA, Dominitz JA, Gao Y, Yankey N, May FP, Mafi J, Saini SD. Development and validation of a new ICD-10-based screening colonoscopy overuse measure in a large integrated healthcare system: a retrospective observational study. BMJ Qual Saf. 2022 Oct 3:bmjqs-2021-014236. doi: 10.1136/bmjqs-2021-014236. Epub ahead of print.
PMID: 36192148
Cohen-Mekelburg S, Van T, Wallace B, Berinstein J, Yu X, Lewis J, Hou J, Dominitz JA, Waljee AK. The association between non-steroidal anti-inflammatory drug use and inflammatory bowel disease exacerbations: a true association or residual bias? Am J Gastroenterol. 2022 Aug 12. doi: 10.14309/ajg.0000000000001932. Epub ahead of print.
PMID: 35970816
Thai T, Louden DKN, Adamson R, Dominitz JA, Doll JA. Peer evaluation and feedback for invasive medical procedures: a systematic review. BMC Med Educ. 2022 Jul 29;22(1):581. doi: 10.1186/s12909-022-03652-9. PMCID: PMC9335975.
PMID: 35906652
Shaukat A, Tuskey A, Rao VL, Dominitz JA, Murad MH, Keswani RN, Bazerbachi F, Day LW; (ASGE Quality Assurance in Endoscopy Committee Chair). Interventions to improve adenoma detection rates for colonoscopy. Gastrointest Endosc. 2022 Jun 6:S0016-5107(22)00248-6. doi: 10.1016/j.gie.2022.03.026. Epub ahead of print.
PMID: 35680469.
Komanduri S, Dominitz JA, Rabeneck L, Kahi C, Ladabaum U, Imperiale TF, Byrne MF, Lee JK, Lieberman D, Wang AY, Sultan S, Shaukat A, Pohl H, Muthusamy VR. GA White Paper: Challenges and Gaps in Innovation for the Performance of Colonoscopy for Screening and Surveillance of Colorectal Cancer. Clin Gastroenterol Hepatol. 2022 Jun 7:S1542-3565(22)00531-6. doi: 10.1016/j.cgh.2022.03.051. Epub ahead of print.
PMID: 35688352.
Liang PS, Williams JL, Dominitz JA, Corley DA, Zauber AG. Age-stratified prevalence and predictors of neoplasia among US adults undergoing screening colonoscopy in a national endoscopy registry. Gastroenterology. 2022 May 25:S0016-5085(22)00527-3. doi: 10.1053/j.gastro.2022.05.036. Epub ahead of print.
PMID: 35643172.
Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ. Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2022 Apr 26. doi: 10.14309/ajg.0000000000001755. Epub ahead of print.
PMID: 35471415.
Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ. Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2022 Apr 13:S0016-5085(22)00151-2. doi: 10.1053/j.gastro.2022.02.021. Epub ahead of print.
PMID: 35487791.
Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ. Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer. Gastrointest Endosc. 2022 Apr 7:S0016-5107(22)00183-3. doi: 10.1016/j.gie.2022.02.044. Epub ahead of print.
PMID: 35487765.
Gawron AJ, Sultan S, Glorioso TJ, Califano S, Kralovic SM, Jones M, Kirsh S, Dominitz JA. Pre-Endoscopy COVID-19 screening and SARS-CoV-2 nucleic acid amplification testing in the VA Healthcare System: Clinical practice patterns, outcomes, and relationship to procedure volume. Gastrointest Endosc. 2022 Apr 21:S0016-5107(22)00288-7. doi: 10.1016/j.gie.2022.04.018. Epub ahead of print.
PMID: 35461889.
Gawron AJ, Dominitz JA. Editorial: Higher Quality Colonoscopy -Worth the Wait? Clin Transl Gastroenterol. 2022 Mar 16. doi: 10.14309/ctg.0000000000000471. Epub ahead of print.
PMID: 35297791.
Yakovchenko V, Morgan TR, Miech EJ, Neely B, Lamorte C, Gibson S, Beste LA, McCurdy H, Scott D, Gonzalez R, Park A, Powell BJ, Bajaj JS, Dominitz JA, Chartier M, Ross D, Chinman MJ, Rogal SS. Core implementation strategies for improving cirrhosis care in the Veterans Health Administration. Hepatology. 2022 Feb 6. doi: 10.1002/hep.32395. Epub ahead of print.
PMID: 35124820.
Mog AC, Liang PS, Donovan LM, Sayre GG, Shaukat A, May FP, Glorioso TJ, Jorgenson MA, Wood GB, Mueller C, Dominitz JA. Timely Colonoscopy After Positive Fecal Immunochemical Tests in the Veterans Health Administration: A Qualitative Assessment of Current Practice and Perceived Barriers. Clin Transl Gastroenterol. 2022 Jan 19. doi: 10.14309/ctg.0000000000000438. Epub ahead of print.
PMID: 35060937.
Patel SG, May FP, Anderson JC, Burke CA, Dominitz JA, Gross SA, Jacobson BC, Shaukat A, Robertson DJ. Updates on Age to Start and Stop Colorectal Cancer Screening: Recommendations From the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2022 Jan 1;117(1):57-69. doi: 10.14309/ajg.0000000000001548.
PMID: 34962727
Learn more about this publication on Dimensions
2021
Dominitz JA, Fisher DA, Garman KS, Hunt CM, Lieberman D, Muir AJ, Onken JE, Robertson DJ, Sandler RS, Sultan S. In Memoriam: Dawn Tranchino Provenzale, MD, MS (August 18, 1955-April 22, 2021). Gastroenterology. 2021 Dec 22:S0016-5085(21)04094-4. doi: 10.1053/j.gastro.2021.12.258. Epub ahead of print.
PMID: 34990569.
O'Hare AM, Berry K, Fan VS, Crothers K, Eastment MC, Dominitz JA, Shah JA, Green P, Locke E, Ioannou GN. Age differences in the association of comorbid burden with adverse outcomes in SARS-CoV-2. BMC Geriatr. 2021 Jul 6;21(1):415. doi: 10.1186/s12877-021-02340-5. PMCID: PMC8258273.
PMID: 34229623.
Ioannou GN, O'Hare AM, Berry K, Fan VS, Crothers K, Eastment MC, Locke E, Green P, Shah JA, Dominitz JA. Trends over time in the risk of adverse outcomes among patients with SARS-CoV-2 infection. Clin Infect Dis. 2021 May 11:ciab419. doi: 10.1093/cid/ciab419. Epub ahead of print.
PMID: 33973000.
Rogal SS, Yakovchenko V, Gonzalez R, Park A, Beste LA, Rozenberg-Ben-Dror K, Bajaj JS, Scott D, McCurdy H, Comstock E, Sidorovic M, Gibson S, Lamorte C, Nobbe A, Chartier M, Ross D, Dominitz JA, Morgan TR. The Hepatic Innovation Team Collaborative: A Successful Population-Based Approach to Hepatocellular Carcinoma Surveillance. Cancers (Basel). 2021 May 7;13(9):2251. doi: 10.3390/cancers13092251. PMCID: PMC8125814.
PMID: 34067177.
Ioannou GN, Green P, Fan VS, Dominitz JA, O'Hare AM, Backus LI, Locke E, Eastment MC, Osborne TF, Ioannou NG, Berry K. Development of COVIDVax Model to Estimate the Risk of SARS-CoV-2-Related Death Among 7.6 Million US Veterans for Use in Vaccination Prioritization. JAMA Netw Open. 2021 Apr 1;4(4):e214347. doi: 10.1001/jamanetworkopen.2021.4347.
PMID: 33822066.
Ioannou GN, Liang PS, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Eastment MC, Fan VS, Dominitz JA. Cirrhosis and SARS-CoV-2 infection in US Veterans: risk of infection, hospitalization, ventilation and mortality. Hepatology. 2020 Nov 21. doi: 10.1002/hep.31649. Epub ahead of print.
PMID: 33219546.
2020
Ioannou GN, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Eastment MC, Dominitz JA, Fan VS. Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among 10 131 US Veterans With SARS-CoV-2 Infection. JAMA Netw Open. 2020 Sep 1;3(9):e2022310. doi: 10.1001/jamanetworkopen.2020.22310. PMCID: PMC7512055.
PMID: 32965502.
Fan VS, Dominitz JA, Eastment MC, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Ioannou GN. Risk Factors for testing positive for SARS-CoV-2 in a national US healthcare system. Clin Infect Dis. 2020 Oct 27:ciaa1624. doi: 10.1093/cid/ciaa1624. Epub ahead of print. PMCID: PMC7665412.
PMID: 33105485.
Rogal SS, Yakovchenko V, Morgan T, Bajaj JS, Gonzalez R, Park A, Beste L, Miech EJ, Lamorte C, Neely B, Gibson S, Malone PS, Chartier M, Taddei T, Garcia-Tsao G, Powell BJ, Dominitz JA, Ross D, Chinman MJ. Getting to implementation: a protocol for a Hybrid III stepped wedge cluster randomized evaluation of using data-driven implementation strategies to improve cirrhosis care for Veterans. Implement Sci. 2020 Oct 21;15(1):92. doi: 10.1186/s13012-020-01050-7. PMCID: PMC7579930.
PMID: 33087156.
Eastment MC, Berry K, Locke E, Green P, O'Hare A, Crothers K, Dominitz J, Fan VS, Shah JA, Ioannou GN. Body mass index (BMI) and outcomes of SARS-CoV-2 among US veterans. Obesity (Silver Spring). 2020 Dec 18. doi: 10.1002/oby.23111. Epub ahead of print.
PMID: 33336934.
2019
Beste LA, Ioannou GN, Chang MF, Forsberg CW, Korpak AM, Boyko EJ, Sporleder JL, Smith NL, Maynard C, Chartier M, Dominitz JA. Prevalence of Hepatitis B Virus Exposure in the Veterans Health Administration and Association With Military-Related Risk Factors. Clin Gastroenterol Hepatol. 2020 Apr;18(4):954-962.e6. doi: 10.1016/j.cgh.2019.07.056. Epub 2019 Aug 5.
PMID: 31394284.
